Get Informed: Lomotil
Active Ingredient(s)
Atropine with Diphenoxylate
What does it do?
This product is used in the treatment of diarrhea. It works by inhibiting the rapid movement the intestines.
- Last Text Update:
- 2010-Jul-31 2:05 PM
- Last Data Update:
- 2010-Jul-30 9:16 PM
Other Names
- Lomotil
- Lonox
- Diphenoxylate / Atropine
- CO-Phenotrope
- Atropine with Diphenoxylate
- Dymotil
How Safe Is It?
- Your Risk Rating
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- Average Risk Rating
-
- Pregnancy Category
- C
- Black Box Warning:
- No
Facts & Figures
- Date Approved
- 15 Sep 1960
- Est US Patients*
- 128,900
- Generic Available
- Yes
- OTC Available
- No
User Age Distribution*
< 21
21-39
40-59
60+
Age (Years)
* Estimated number of US people currently taking Lomotil or its active ingredient based on population adjusted patient numbers registered with iGuard.org.
Recent alerts for Lomotil
There have been no iGuard.org alerts regarding Lomotil during the past year.
Lomotil Safety Report
Learn more about iGuard's risk ratings
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What is Lomotil used for?
iGuard is currently tracking more than 950 patients that use Lomotil (or similar drugs with the same active ingredient(s)). Use the table below to learn why iGuard users take this product; click on any underlined condition to get information on other medications used for treatment.
| Disease / Condition | % | Average Severity |
|---|---|---|
| Diarrhea | 73% |
mild
severe
|
| Irritable Bowel | 37% |
mild
severe
|
| Crohn's Disease | 3% |
mild
severe
|
| Ulcerative Colitis | 3% |
mild
severe
|
How well does Lomotil work?
iGuard regularly polls our more than 950 users taking Lomotil (or similar drugs with the same active ingredient(s)) using the Treatment Satisfaction Questionnaire for Medications (TSQM) . This feedback is continuously updated in tables below for the benefit of the iGuard community. To request scores for specific patient subgroups, please contact research@iGuard.org.
Average Satisfaction Score
(out of 10)
Average Effectiveness Score
(out of 10)
- 86%
- of patients are confident that the good things about Lomotil outweigh the bad things.
- 6%
- of patients wish they were told more before they started taking Lomotil.
Common Side Effects of Lomotil
iGuard regularly polls our more than 950 users taking Lomotil (or similar drugs with the same active ingredient(s)) to monitor the development and frequency of side-effects. This feedback is continuously updated in tables and graphs below for the benefit of the iGuard community.
20% of patients experience side-effects on Lomotil
< 1% of patients experience significant side-effects on Lomotil
Most Common Side Effects...
-
Constipation
-
Dryness
-
Drowsiness
-
Restlessness
-
Anxiety
-
Swelling/Edema
-
Headache
-
= 10%
Global Patient Feedback for Lomotil (Atropine with Diphenoxylate) ( Post a comment )
Question/Comment:
im 24 yrs old and fall in the 2 percent of people with ibs. no medicine helps i take a real big overdose of 18 pills at once for 4 yrs now and most of the time it fails to help and when it does it only works for 5 hrs. most people would think i will die from that many at once. but when in fact the over 50 medical doctors i been to all gastrointestinal ologist have mixed reviews. but most make me stay in a worthless hospital for up to 4-5 days and see how my body reacts to the huge over dose in lomotil. and they say that my body is used to the overdose you are probly wondering why i would tell people this. i am telling you people this that what i have done the past 4 yrs even though i been sick for 16 yrs is that dont do it. it would kill most people. overdose is bad even to a small level of it but i take almost 3 times the dose. just bc the docts say it wont hurt or kill me doesnt mean it wont. doctors are just humans like all of us. i do it bc i have no choice its eathier i risk it for the past 4 yrs or i am going to b hospitalized for the rest of my life. i have had over 300 medications for it and some medications that really wouldnt make sense to the normal person but as of like me the doctors are also desprite. when u r sick like me 24 yrs old and in a 4 day time spane go to the bathroom over 100 150 times. it really doesnt bother your mind set on the medication. so if u fall in the cursed uncurable unmedicated 2 % i feel sorry for you. if you fall in the helpfull percent i envy you. so the next time you r sick and u feel hopless and you take your medicine and return normal. just remember ur not the only person that has this problem and there is people out there like i that are far worse then you. andrew 24yrs old
Male Source: iGuard United States
Posted: 2010-06-14 10:26:01
Question/Comment:
I had 2/3 of my large intestine removed 3+ years ago because of a colonoscopy with precancerous growths. I have had crohn's for over 25 years. I was unaware that I would have chronic diarhhea after surgery, and absolutely cannot live without my lomotil. I have never had any side effects and it allows me to leave my house daily and have a normal life. My crohn's is very under control, the diarhhea is an issue I deal with daily but take 2-4 tablets to function. It is a life saver for me.
Female - 62 years old
62 year old Female – Source: iGuard United States
Posted: 2010-04-19 19:37:33
Question/Comment:
I have been on Lomotil for 10 years. It has helped me to have a "normal" life. I had a botched surgery that left me incontinent. W/O Lomotil, I would not be able to leave the house. I also developed IBS after the botched surgey, a female one was not done correctly. I am grateful for Lomotil, an old drug that has been tried and true...
64 year old Female – Source: iGuard United States
Posted: 2010-04-12 17:31:46
Question/Comment:
I have Crohns Disease and have been on Lomotil for 4 years now. It has helped me in the past, but now I've been taking 2-3 (2.5 mg.) pills at a time and it doesn't seem to be helping anymore. I'm wondering if you can become immune to it? I am going to ask my doctor at my next visit, because I used to take one pill in the early morning (7:00 a.m.) and then another around 11:00 a.m., and they helped, but now I've had to increase my dosage and they are not working anymore. Has anyone else became immune to this medication?
47 year old Female – Source: iGuard United States
Posted: 2009-07-08 09:19:36
iGuard Answer/Reply:
It is possible to develop a tolerance to Lomotil. A tolerance would cause your body to need more of the medication to achieve the same effect. However, you are close to the maximum daily dose taken on a regular basis so you should not increase your dose without first talking to your doctor. There may be something else could be causing the medication to not work as well for you. It is possible you are having a flare-up of your Crohn's Disease. Coming out of remission could also cause the Lomotil to not work as well. Make an appointment with your physician to discuss your increased symptoms.
Posted: 2009-07-09 01:30:11
Question/Comment:
I had my large intestine taken out about 4 years and now have a inner pouch. I had UC for over 12 years, and with these surgeries and taking Lomotil I have a normal life. I take it 4 times a day. 20 minutes before each meal and before bed.
44 year old Female – Source: iGuard United States
Posted: 2009-06-01 11:08:49
You may post comments for the benefit of other patients or post questions other patients might be able to answer. Comments are submitted for possible publication on the condition that they may be edited. Only your age and gender will be published with your comment, although your other user details will be securely recorded for verification purposes.
Comments may be either questions or answers to previously posted questions. Any iGuard.org user may post questions and reply.
11
Patient Comments About
Lomotil